838838-37-2Relevant academic research and scientific papers
Stereoselective synthesis by double reductive amination ring closure of novel aza-heteroannulated sugars
Laventine, Dominic M.,Davies, Michelle,Evinson, Emma L.,Jenkins, Paul R.,Cullis, Paul M.,García, Marcos D.
experimental part, p. 4766 - 4774 (2009/10/09)
We present here the stereoselective synthesis of a series of 2/3-N-pyrrolidine derivatives of glycosides produced by diastereoselective double reductive amination ring closure of 1,4-dicarbonyl compounds. These precursors were produced by tandem ozonolysi
Ring-closing double reductive amination route to aza-heteroannulated sugars
Laventine, Dominic M.,Davies, Michelle,Evinson, Emma L.,Jenkins, Paul R.,Cullis, Paul M.,Fawcett, John
, p. 307 - 310 (2007/10/03)
1,4-Dicarbonyl derivatives of glycosides are produced by ozonolysis or Wacker oxidation. A stable ozonide is isolated and a carbonyl group reduced whilst maintaining the ozonide functionality. The 1,4-dicarbonyl compounds are converted to various N-substi
