838845-69-5

Basic information

• Product Name: 6-ACETYL-5-(4-CHLOROPHENYL)-1,3,7-TRIMETHYL-5,8-DIHYDROPYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE
• Synonyms: 6-ACETYL-5-(4-CHLOROPHENYL)-1,3,7-TRIMETHYL-5,8-DIHYDROPYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE
• CAS NO: 838845-69-5
• Molecular Formula: C18H18ClN3O3
• Molecular Weight: 359.81
• Mol File: 838845-69-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-ACETYL-5-(4-CHLOROPHENYL)-1,3,7-TRIMETHYL-5,8-DIHYDROPYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-ACETYL-5-(4-CHLOROPHENYL)-1,3,7-TRIMETHYL-5,8-DIHYDROPYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE(838845-69-5)
• EPA Substance Registry System: 6-ACETYL-5-(4-CHLOROPHENYL)-1,3,7-TRIMETHYL-5,8-DIHYDROPYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE(838845-69-5)

Safety Data

• Hazardous Substances Data: 838845-69-5(Hazardous Substances Data)

Upstream product

• 6642-31-5 6-Amino-1,3-dimethylbarbituric acid 
• 104-88-1 4-chlorobenzaldehyde 
• 123-54-6 acetylacetone 

Relevant articles and documents

Dihydropyrido[2,3-d]pyrimidines as a new class of antileishmanial agents

A series of dihydropyrido[2,3-d]pyrimidines have been synthesized and screened for its in vitro antileishmanial activity profile in promastigote and amastigote models. Compounds 2a-2l have shown 83-100% inhibition against promastigotes and 79-100% inhibition against amastigotes at a concentration of 50 μg/mL.

First report on the abnormal dearylation/alkylation reaction in one-pot hantzch synthesis with 6-amino-1,3-dimethyl uracil

First report on the abnormal dearylation/dealkylation reaction occurring during dehydrogenation in one-pot, three-component condensation of dihydropyrido[2,3-d]pyrimidines.