83889-48-9

Upstream product

• 7569-26-8 chloromethyl p-tolylsulfone 
• 6616-69-9 dl-6aα,7,10,10aα-Tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-6H-dibenzo[b,d]pyran-9(8H)-on 
• 500-66-3 Olivetol 
• 6616-69-9 11-nor-9-keto-6a,10a-cis-HHC 
• 61597-37-3 4-(1-hydroxy-1-methylethyl)-1-methoxy-1,4-cyclohexadiene 

Relevant academic research and scientific papers

The synthesis of some 11-substituted tetrahydrocannabinol metabolites

9-Bromo-11-oxo-hexahydrocannabinol (5) was prepared from the ketocannabinoid 3b via the epoxysulfone 4.The dehydrobromination of the bromoaldehyde 5 could be controlled to give either the thermodinamically more stable Δ8-aldehyde 2c, or the Δ9-aldehyde 1c by an intramolecularly assisted elimination.Reduction of the unsaturated aldehydes gave the allylic alcohol metabolites 2a and 1a, respectively.