83901-03-5Relevant academic research and scientific papers
A very mild and quantitative oxidation of cephalosporins with dimethyldioxirane
Gunda, Tamas E.,Tamas, Laszlo,Salyi, Szabolcs,Nemes, Csaba,Sztaricskai, Ferenc
, p. 7111 - 7114 (1995)
The cephalosporins 1-3 and Δ2-cephem 4 were oxidized in quantative yields to their sulfones with dimethyldioxirane. While in the case of 2-methylene-cephems (5,6) the exocyclic double bond oxidized simultaneously to the corresponding epoxide, t
SYNTHESIS AND 1,3-DIPOLAR CYCLOADDITIONS OF 2-METHYLENECEPHALOSPORINS
Jaszberenyi J. Csaba,Pitlik Janos,Kollar Katalin,Petrikovics Ilona,Erdoedi-Koever Katalin,Batta Gyula
, p. 81 - 98 (2007/10/02)
Cephalosporin R- and S-sulphoxides were prepared.The S-sulphoxides gave Mannich-reaction resulting in the formation of 2-methylenecephalosporins.These electrom-deficient dienes underwent 1,3-dipolar cycloadditions with diazoalkanes in a chemo- and regiosp
