83916-71-6

Upstream product

• 5328-37-0 L-arabinose 
• 95-64-7 4-amino-o-xylene 
• 130543-48-5 (2S,3S,4R)-3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-5-(3,4-dimethyl-phenylamino)-pentane-1,2-diol 
• 922-65-6 divinylcarbinol 
• 100017-22-9 (S)-1-[(R)-oxiran-2-yl]prop-2-enol 
• 130543-39-4 (2R,3S)-1-(3,4-Dimethyl-phenylamino)-pent-4-ene-2,3-diol 
• 50-69-1 D-ribose 
• 906331-23-5 5-(3,4-dimethyl-anilino)-5-deoxy-L-arabitol 
• 109215-18-1 5-(3,4-dimethyl-anilino)-5-deoxy-D-arabitol 

Downstream Products

• 130543-40-7 Acetic acid (1R,2R,3S)-2,3,4-triacetoxy-1-{[acetyl-(3,4-dimethyl-phenyl)-amino]-methyl}-butyl ester 
• 21037-26-3 N-ribityl-2-phenylazo-4,5-dimethylaniline 
• 146-17-8 O^5'-phosphono-riboflavin 
• 83-88-5 riboflavin 
• 6286-17-5 1-[6-(4-nitro-phenylazo)-3.4-dimethyl-anilino]-1-deoxy-L-arabitol 

Relevant academic research and scientific papers

Site-Selective Synthesis of 15N- and 13C-Enriched Flavin Mononucleotide Coenzyme Isotopologues

Flavin mononucleotide (FMN) is a coenzyme for numerous proteins involved in key cellular and physiological processes. Isotopically labeled flavin is a powerful tool for studying the structure and mechanism of flavoenzyme-catalyzed reactions by a variety of techniques, including NMR, IR, Raman, and mass spectrometry. In this report, we describe the preparation of labeled FMN isotopologues enriched with 15N and 13C isotopes at various sites in the pyrazine and pyrimidine rings of the isoalloxazine core of the cofactor from readily available precursors by a five-step chemo-enzymatic synthesis.

The asymmetric epoxidation of divinyl carbinols: Theory and applications

The asymmetric epoxidation of symmetric divinyl carbinols is illustrative of a reaction process that combines an initial asymmetric synthesis with a subsequent kinetic resolution to provide products with extraordinary levels of enantiomeric purity. The application of this process to the asymmetric synthesis of natural products is presented herein.