83927-06-4

Upstream product

• 1918-82-7 2-vinylthiophene 
• 6773-29-1 dimethyl diazomalonate 

Downstream Products

• 1130593-84-8 (2R,5R)-dimethyl 2-styryl-5-(thien-2-yl)tetrahydrofuran-3,3-dicarboxylate 
• 1130593-90-6 (2R,5R)-dimethyl 2-phenyl-5-(thien-2-yl)tetrahydrofuran-3,3-dicarboxylate 
• 1130593-82-6 (2R,5R)-dimethyl 2-(4-methoxyphenyl)-5-(thien-2-yl)tetrahydrofuran-3,3-dicarboxylate 
• 1235889-81-2 (2R,5R)-dimethyl 2-(4-fluorophenyl)-1-(2-methoxybenzyl)-5-(thiophen-2-yl)pyrrolidine-3,3-dicarboxylate 
• 1235889-86-7 (2R,5R)-dimethyl 1-(2-methoxybenzyl)-2-phenyl-5-(thiophen-2-yl)pyrrolidine-3,3-dicarboxylate 
• 1181823-88-0 C₂₁H₂₃NO₄S 
• 1435466-98-0 C₃₀H₃₁NO₅S 
• 1577201-86-5 dimethyl 2-((N,4-dimethylphenyl)sulfonamido)-3-pentyl-4-(thiophen-2-yl)cyclopent-2-ene-1,1-dicarboxylate 
• 1577201-88-7 dimethyl 2-((N,4-dimethylphenyl)sulfonamido)-3-phenyl-4-(thiophen-2-yl)cyclopent-2-ene-1,1-dicarboxylate 

Relevant academic research and scientific papers

(3 + 2)-Cycloaddition of Donor-Acceptor Cyclopropanes with Selenocyanate: Synthesis of Dihydroselenophenes and Selenophenes

We present a Lewis-acid-catalyzed (3 + 2)-cycloaddition of donor-acceptor cyclopropanes and selenocyanate (as its tetramethylammonium salt) for the synthesis of dihydroselenophenes. The transformation proceeded with moderate to excellent yields and showed a high functional group tolerance. Further oxidation using DDQ delivered selenophenes.

(3+2)-Cycloaddition of Donor-Acceptor Cyclopropanes with Thiocyanate: A Facile and Efficient Synthesis of 2-Amino-4,5-dihydrothiophenes

An easy and efficient route to obtain 2-amino-4,5-dihydrothiophenes is presented. A formal (3+2)-cycloaddition of donor-acceptor cyclopropanes and ammonium thiocyanate catalyzed by Yb(OTf) 3delivers the desired products in good to excellent yields. A broad range of functional groups is tolerated during this process.