83938-75-4

Usage

General Description

1(3H)-Isobenzofuranone, 3,3-bis[4-hydroxy-3-(1-methylethyl)phenyl]-, also known as UV-326, is a chemical compound used as a UV filter in sunscreens and other personal care products. It is a white to off-white crystalline powder that is insoluble in water but soluble in organic solvents. UV-326 is known for its ability to absorb and dissipate UV radiation, helping to protect the skin from the harmful effects of the sun. However, there have been concerns about its potential to disrupt hormone function and its impact on the environment, leading to regulatory restrictions in some regions. Nonetheless, UV-326 continues to be used in a variety of sun protection products.

Upstream product

• 85-44-9 phthalic anhydride 
• 88-69-7 2-(1-methylethyl)phenol 
• 83938-70-9 2-(4-hydroxy-3-isopropylbenzoyl)benzoic acid 

Downstream Products

• 83938-70-9 2-(4-hydroxy-3-isopropylbenzoyl)benzoic acid 
• 83938-76-5 3-(4-hydroxy-5-isopropyl-2-methylphenyl)-3-(4-hydroxy-3-isopropylphenyl)phthalide 
• 83938-72-1 3-acetoxy-3-(4-acetoxy-3-isopropylphenyl)phthalide 
• 83938-78-7 4-(4-hydroxy-3-isopropylphenyl)-2-phenyl-1(2H)-phthalazinone 
• 83938-79-8 2-(3-Bromo-4-hydroxy-5-isopropylbenzoyl)benzoic acid 
• 83938-71-0 methyl 2-(4-hydroxy-3-isopropylbenzoyl)benzoate 
• 83938-77-6 4-(4-hydroxy-3-isopropylphenyl)-1(2H)-phthalazinone 
• 83938-73-2 4-hydroxy-3-isopropylbenzophenone 

Relevant academic research and scientific papers

NbCl5 Promoted the Efficient Synthesis of Phthalein Derivatives: Optical Characterization and Solvatochromic Effect

Organic dyes derived from phthaleins have a large number of industrial applications and can be synthesized using a Lewis acid by Friedel–Crafts acylation, followed by an addition reaction to the carbonyl compound. This work aims to investigate the use of NbCl5 as a catalyst for the acylation reaction. The behavior of the phthalein derivatives in several solvents and when subjected to different pH conditions was studied. These compounds showed a color-changing effect depending on the pH and solvent, making them useful for applications as indicators. The phthaleins change their conformations depending on the condition of the medium. Photophysical studies of these compounds were carried out through their UV–Vis absorption spectra. Here, we show the umbrella-like conformation change of phthalein derivatives that depend on the solvent and the pH of the medium.

A facile synthesis of phthalein indicator dyes

The use of methanesulfonic acid offers a novel and highly efficient method for the synthesis of phthalein indicator dyes in excellent yields on an industrial scale.

Oral care compositions with color changing indicator

The invention describes color changing toothpastes and mouthwashes which contains acid-base indicator(s) for interaction with the oral cavity to provide a color change indicative of treatment time.

Syntheses and Reactivity of 2-Aroylbenzoic Acids, II. 2-(4-Hydroxy-3-isopropylbenzoyl)benzoic Acid

Die Friedel-Crafts-Acylierung von 2-Isopropylphenol mit Phthalsaeureanhydrid liefert nur die 2-(4-Hydroxy-3-isopropylbenzoyl)benzoesaeure (1) vom p-Acylphenol-Typ.Die Reaktionsfaehigkeit der Saeure 1 wurde untersucht, und ihre Derivate 2 - 10 werden besch