83948-33-8Relevant academic research and scientific papers
Dual activation in asymmetric allylsilane addition to chiral N-acylhydrazones: Method development, mechanistic studies, and elaboration of homoallylic amine adducts
Friestad, Gregory K.,Korapala, Chandra Sekhar,Ding, Hui
, p. 281 - 289 (2007/10/03)
Chiral N-acylhydrazones derived from commercially available 4-benzyl-2-oxazolidinone provide a rigid, conformationally restricted template to impart facial selectivity in additions to C=N bonds. In the presence of indium(III) trifluoromethanesulfonate [In
A NEW SYNTHESIS OF PRIMARY AMINES FROM DIARYLIDENESULFAMIDES
Davis, Franklin A.,Giangiordano, Mark A.,Starner, William E.
, p. 3957 - 3960 (2007/10/02)
Addition of organometallic reagents to diarylidenesulfamides affords, after hydroylsis, primary amines illustrating the application of sulfamides as amino protecting groups.
Preparation of Primary Amines and 2-Azetidinones via N-Trimethylsilyl Imines
Hart, David J.,Kanai, Ken-ichi,Thomas, Dudley G.,Yang, Teng-Kuei
, p. 289 - 294 (2007/10/02)
Nonenolizable aldehydes react with lithium bis(trimethylsilyl)amide at ambient temperatures to afford solutions of N-trimethylsilyl aldimines.Treatment of these solutions with Grignard reagents or alkyllithiums followed by an aqueous workup gives primary amines in moderate to excellent yields.Treatment of N-trimethylsilyl aldimines with ester enolates provides an expedient route to 1-unsubstituted 2-azetidinones.
New Approach to Lythraceae Alkaloids: Total Synthesis of (+/-)-Vertaline
Hart, David J.,Kanai, Ken-ichi
, p. 1555 - 1560 (2007/10/02)
A new approach to Lythraceae alkaloids is described within the context of a total synthesis of (+/-)-vertaline (2).The use of N-silyl imines in the preparation of benzylic amines as well as a stereoselective bicycloannelation approach to the synthesis of quinolizidinones is discussed.
