83966-94-3 Usage
Chemical structure
1-(2-bromo-2-deoxy-β-D-arabinofuranosyl)-5-iodocytosine hydrochloride is a nucleoside analog with a modified sugar moiety and a halogenated base.
Antiviral activity
The compound exhibits potent activity against various types of viral infections, including herpes and hepatitis.
Mechanism of action
It works by inhibiting the replication of viral DNA, thus preventing the spread of the virus.
Development of antiviral drugs
The compound is used in the development of antiviral drugs due to its effectiveness in treating viral infections.
Research tool
It serves as a research tool in the study of viral diseases, helping to understand the mechanisms of viral replication and the development of new antiviral therapies.
Hydrochloride salt form
The hydrochloride salt form of the compound increases its water solubility, making it more suitable for therapeutic use.
Chemical properties
The compound is a halogenated nucleoside analog with a modified sugar moiety, which contributes to its antiviral activity.
Applications
It is used in the treatment of viral infections and in the development of new antiviral drugs and therapies.
Safety and side effects
As with any drug, the safety and side effects of 1-(2-bromo-2-deoxy-β-D-arabinofuranosyl)-5-iodocytosine hydrochloride should be carefully considered and monitored during its use.
Regulatory approval
The compound may require regulatory approval for its use as a therapeutic agent, depending on the specific application and jurisdiction.
Check Digit Verification of cas no
The CAS Registry Mumber 83966-94-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,9,6 and 6 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 83966-94:
(7*8)+(6*3)+(5*9)+(4*6)+(3*6)+(2*9)+(1*4)=183
183 % 10 = 3
So 83966-94-3 is a valid CAS Registry Number.
83966-94-3Relevant academic research and scientific papers
Nucleosides. 123. Synthesis of Antiviral Nucleosides: 5-Substituted 1-(2-Deoxy-2-halogeno-β-D-arabinofuranosyl)cytosines and -uracils. Some Structure-Activity Relationships
Watanabe, Kyoichi A.,Su, Tsann-Long,Klein, Robert S.,Chu, Chung K.,Matsuda, Akira,et al.
, p. 152 - 156 (2007/10/02)
The syntheses of several 2'-halogeno-5-substituted-arabinofuranosylcytosines and -uracils are described, and relationships of structure to anti herpes virus activity in vitro were examined.Those arabinonucleosides containing the 2'-fluoro function exhibit
5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides
-
, (2008/06/13)
Pyrimidine nucleosides exhibiting anti-viral and anti-tumor effects have the formula STR1 wherein A is OR3, SR3, NR3 R4 or NHacyl wherein R3 and R4 are the same or different and are hydroge
