84024-11-3Relevant articles and documents
Microwave assisted Perkin reaction for the synthesis of α-arylidine-γ-phenyl-Δ, β, γ-butenolides
Deo, Sujata,Chaudhari, Tanishq,Inam, Farhin
, p. 363 - 367 (2014/05/06)
Perkin condensation with subsequent intramolecular lactonisation as one pot synthesis of α-arylidine-γ-phenyl-Δ,β,γ- butenolides have been studied under microwave irradiation. The butenolides are cleaved to give keto acids, which are the precursors of pericarbonyl lactone lignans possessing variety of biological activities. Syntheses of butenolides have been carried out using pyridine as a catalyst under microwave conditions. The generality of this protocol has been demonstrated by synthesizing a variety of substituted butenolides in excellent yields, short reaction time and with good purity compared to those under classical thermal conditions. All the products have been characterized by their IR, 1H NMR and UV spectral values.
Synthesis of 1-phenyl naphthalene and pericarbonyl lignans
Deo, Sujata,Inam, Farhin,Mahashabde,Jadhav
experimental part, p. 3362 - 3368 (2010/11/16)
The approach towards synthesis of 1-phenyl naphthalene and pericarbonyl lactone by cyclization of Perkin condensation product, ∝- arylidene β-benzoyl propionic acid with polyphosphoric acid and concentrated sulphuric acid can be achieved in one step.
