84028-92-2

Basic information

• Product Name: (2R,2'R)-2-(2-Ethylpiperidino)-3-phenyl-propionsaeure-methylester
• CAS NO: 84028-92-2
• Molecular Weight: 275.391
• Mol File: 84028-92-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R,2'R)-2-(2-Ethylpiperidino)-3-phenyl-propionsaeure-methylester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,2'R)-2-(2-Ethylpiperidino)-3-phenyl-propionsaeure-methylester(84028-92-2)
• EPA Substance Registry System: (2R,2'R)-2-(2-Ethylpiperidino)-3-phenyl-propionsaeure-methylester(84028-92-2)

Safety Data

• Hazardous Substances Data: 84028-92-2(Hazardous Substances Data)

Upstream product

• 84028-86-4 methyl (L)-3-phenyllactate triflate 
• 22160-08-3 (-)-R-2-ethylpiperidine 
• 13673-95-5 (S)-methyl 2-hydroxy-3-phenylpropanoate 

Relevant articles and documents

Amino Acids, 4 - Enantioselective Synthesis of N-Substituted α-Amino Carboxylic Acids from α-Hydroxy Carboxylic Acids

With primary and secondary amines, the (S)-α-(trifluoromethylsulfonyloxy) carboxylates (S)-3 afford in an SN2 reaction the N-substituted (R)-α-amino carboxylates (R)-5, (R)-9, and (R)-12, resp.The rates of α-substituted ethyl propionates decrease in the order of the substituents triflate (3a) >> bromide (8a) > mesylate (7a) >= tosylate (7b) > chloride (8b); in the reactions with amines, decreasing reactivity affords increasing racemisation and elimination as a consequence of the more drastic conditions which are required