84040-08-4Relevant academic research and scientific papers
Intramolecular Catalysis in the Reaction of 1-Fluoro-2,4-dinitrobenzene with Diamines in Benzene
Guanti, Giuseppe,Petrillo, Giovanni,Thea, Sergio,Pero, Francesca
, p. 2764 - 2771 (2007/10/02)
A kinetic investigation of the reaction of 1-fluoro-2,4-dinitrobenzene (FDNB) with saturated diamines in benzene shows that, when the two amino groups are suitable placed with respect to each other, catalysis by a second diamine molecule is kinetically insignificant throughout the diamine concentration range examined.A comparison with the reactivity of the same diamines towards 1-chloro-2,4-dinitrobenzene (CNDB) suggests that the rate-determining step is nucleophilic attack also for the FDNB system.This behaviour is attributed to efficient intramolecular assistance of the second amino group of a diamine molecule to decomposition of the tetrahedral reaction intermediate.
