840488-96-2Relevant academic research and scientific papers
Asymmetric alkylation of remote C(sp3)-H bonds by combining proton-coupled electron transfer with chiral Lewis acid catalysis
Yuan, Wei,Zhou, Zijun,Gong, Lei,Meggers, Eric
, p. 8964 - 8967 (2017)
The catalytic asymmetric alkylation of the remote, unactivated δ-position of N-alkyl amides was enabled by the combination of visible-light-induced proton-coupled electron transfer, 1,5-hydrogen atom transfer, and chiral Lewis acid catalysis in up to 82% yield and up to 97% ee.
