840490-22-4Relevant academic research and scientific papers
Synthesis and study of antiviral and anti-radical properties of aminophenol derivatives
Shadyro,Ksendzova,Polozov,Sorokin,Boreko,Savinova,Dubovik,Bizunok
, p. 2420 - 2423 (2008/09/21)
A number of sterically-hindered o-aminophenol derivatives have been synthesized, and their antiviral activity in parallel with reactivity towards commonly encountered free-radical intermediates was investigated. Of the compounds tested, the highest activity in suppressing replication of Herpes simplex type l viruses was displayed by N-acyl and N-aryl derivatives of 4,6-di-tert-butyl-2-aminophenol, which were able to interact with organic free radicals and, at the same time, manifested low reactivity towards reactive oxygen species.
