840538-72-9Relevant academic research and scientific papers
Indole-glucosides as novel sodium glucose co-transporter 2 (SGLT2) inhibitors. Part 2
Zhang, Xiaoyan,Urbanski, Maud,Patel, Mona,Cox, Geoffrey G.,Zeck, Roxanne E.,Bian, Haiyan,Conway, Bruce R.,Beavers, Mary Pat,Rybczynski, Philip J.,Demarest, Keith T.
, p. 1696 - 1701 (2007/10/03)
A series of indole-O-glucosides and C-glucosides was synthesized and evaluated in SGLT1 and SGLT2 cell-based functional assays. Compounds 2a and 2o were identified as potent SGLT2 inhibitors and screened in ZDF rats.
