840541-41-5

Upstream product

• 840541-40-4 1-benzenesulfonyl-4-bromo-3-(4-ethyl-benzyl)-1H-indole 
• 16331-45-6 p-ethylbenzoyl chloride 
• 52488-36-5 4-bromo-1H-indole 
• 840541-39-1 (1-benzenesulfonyl-4-bromo-1H-indol-3-yl)-(4-ethyl-phenyl)-methanone 
• 840541-38-0 (4-bromo-1H-indol-3-yl)-(4-ethyl-phenyl)-methanone 

Downstream Products

• 880872-16-2 1-(tert-Butyl-dimethyl-silanyl)-3-(4-ethyl-benzyl)-4-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-1H-indole 
• 880872-15-1 4-bromo-1-(tert-butyl-dimethyl-silanyl)-3-(4-ethyl-benzyl)-1H-indole 

Relevant academic research and scientific papers

Indole-glucosides as novel sodium glucose co-transporter 2 (SGLT2) inhibitors. Part 2

A series of indole-O-glucosides and C-glucosides was synthesized and evaluated in SGLT1 and SGLT2 cell-based functional assays. Compounds 2a and 2o were identified as potent SGLT2 inhibitors and screened in ZDF rats.