84072-07-1Relevant academic research and scientific papers
Stereo- and regio-selective Ti-mediated radical cyclization of epoxy-alkenes: Synthesis of the A and C ring synthons of paclitaxel
Nakai, Kazuoki,Kamoshita, Miyuki,Doi, Takayuki,Yamada, Haruo,Takahashi, Takashi
, p. 7855 - 7857 (2001)
We have developed a practical synthetic route for the A and C rings of paclitaxel. The key reaction is a Ti-mediated radical cyclization of an epoxyalkene.
