84082-03-1

Basic information

• Product Name: 3-acetyl-3,5-dihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxyhexopyranoside
• CAS NO: 84082-03-1
• Molecular Formula: C₂₆H₂₇NO₈
• Molecular Weight: 481.4945
• Mol File: 84082-03-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 739.5°C at 760 mmHg
• Flash Point: 401°C
• Density: 1.49g/cm³
• Vapor Pressure: 5.84E-23mmHg at 25°C
• Refractive Index: 1.685
• CAS DataBase Reference: 3-acetyl-3,5-dihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxyhexopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 3-acetyl-3,5-dihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxyhexopyranoside(84082-03-1)
• EPA Substance Registry System: 3-acetyl-3,5-dihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxyhexopyranoside(84082-03-1)

Safety Data

• Hazardous Substances Data: 84082-03-1(Hazardous Substances Data)

Upstream product

• 92999-89-8 1-Chloro-N,O(trifluoroacetyl)-daunosamine 
• 95375-41-0 6,8-Dihydroxy-8-(2-methyl-[1,3]dioxolan-2-yl)-7,8,9,10-tetrahydro-naphthacene-5,12-dione 
• 84073-86-9 (+/-)-4-demethoxy-6-deoxydaunomycinone 
• 84073-92-7 4-demethoxy-6-deoxy-N-trifluoracetyldaunorubicin 
• 84073-92-7 N-[(2S,3S,4S,6R)-6-((1R,3R)-3-Acetyl-3,5-dihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacen-1-yloxy)-3-hydroxy-2-methyl-tetrahydro-pyran-4-yl]-2,2,2-trifluoro-acetamide 

Relevant articles and documents

Regiospecific Total Synthesis of 6-Deoxyanthracyclines: 4-Demethoxy-6-deoxydaunorubicin

A regiospecific approach to 6-deoxyanthracyclinones, which has resulted in the synthesis of the novel anthracycline 4-demethoxy-6-deoxydaunorubicin, is reported.The construction of aglycone entails the coupling of the metalated 1,4-dimethoxynaphthalene with 2-carbomethoxy-4-acetylcyclohexanal.The new aldehyde was prepared from cis tetrahydrophthalic monoester via a regioselective acylation followed by conversion of the carboxylic group to a formyl group.The daunosaminyl glycoside showed on HeLa cells the same cytotoxicity as daunorubicin.