84126-98-7Relevant academic research and scientific papers
3-amino-3-carbamoyloxyalkylacrylic acid intermediates to dihydropyridines
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, (2008/06/13)
A process for preparing a 2-carbamoyloxyalkyl-1,4-dihydropyridine derivative represented by the general formula: STR1 which comprises: (a) reacting a 3-amino-3-carbamoyloxyalkylacrylic acid derivative represented by the general formula: STR2 with a benzylidene compound represented by the general formula: STR3 (b) reacting the 3-amino-3-carbamoyloxyalkylacrylic acid derivative of the general formula II with an aldehyde compound represented by the general formula: STR4 and a β-keto-ester compound represented by the general formula: (c) reacting a 3-carbamoyloxyalkylpropiolic acid derivative represented by the general formula: STR5 with the benzylidene compound of the general formula III and ammonia or its salt; or (d) reacting the 3-carbamoyloyalkylpropiolic acid derivative of the general formula VI with the aldehyde compound of the general formula IV, the β-keto-ester compound of the general formula V and ammonia or its salt.
2-Substituted or unsubstituted aminocarbonyloxyalkyl-1,4-dihydropyridines
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, (2008/06/13)
Novel compounds having vasodilation and hypotensive effects are represented by the formula STR1 where R1 is halogen, nitro, cyano or lower alkoxy; each of R2 and R3 is lower alkyl, lower haloalkyl, lower alkoxyalkyl, aralk
