84127-05-9

Basic information

• Product Name: (2S,4S)-4-[Bis-(4-methoxy-phenyl)-phosphanyl]-2-{[bis-(4-methoxy-phenyl)-phosphanyl]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester
• CAS NO: 84127-05-9
• Molecular Weight: 673.726
• Mol File: 84127-05-9.mol

Chemical Properties

• CAS DataBase Reference: (2S,4S)-4-[Bis-(4-methoxy-phenyl)-phosphanyl]-2-{[bis-(4-methoxy-phenyl)-phosphanyl]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-4-[Bis-(4-methoxy-phenyl)-phosphanyl]-2-{[bis-(4-methoxy-phenyl)-phosphanyl]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester(84127-05-9)
• EPA Substance Registry System: (2S,4S)-4-[Bis-(4-methoxy-phenyl)-phosphanyl]-2-{[bis-(4-methoxy-phenyl)-phosphanyl]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester(84127-05-9)

Safety Data

• Hazardous Substances Data: 84127-05-9(Hazardous Substances Data)

Upstream product

• 61478-27-1 (2S,4S)-N-(tert-butoxycarbonyl)-4-(p-toluenesulfonyloxy)-2-<(p-toluenesulfonyloxy)methyl>pyrrolidine 
• 39864-55-6 Lithium-di-(p-anisyl)-phosphid 

Relevant articles and documents

DESIGN OF METHOXY-SUBSTITUED BPPM ANALOGUES AND THEIR APPLICATION TO THE ASYMMETRIC SYNTHESIS OF N-ACETYLPHENYLALANINE

We described the preparation of methoxy-substitued BPPM ((2S,4S)-N-(tert-butoxycarbonyl)-4-(diphenylphosphino)-2-pyrrolidine) analogues for highly effective asymmetric hydrogenation of (Z)-acetamidocinnamic acid. o-Methoxy-BPPM-Rh+ was very high optical yield (98percent enantiomeric excess (ee), (R)) and p-methoxy-BPPM-Rh+ was very actively catalytic (/=104).On the bases of these result and our respectively control concept, we developed a highly effective chiral ligand (5) for asymmetric synthesis of N-acetylphenylalanine.