84131-75-9

Basic information

• Product Name: 1β,4α-bis(benzyloxy)-1,2,3,4,4aβ,5,8,8aα-octahydronaphthalene
• Synonyms: 1β,4α-bis(benzyloxy)-1,2,3,4,4aβ,5,8,8aα-octahydronaphthalene
• CAS NO: 84131-75-9
• Molecular Weight: 348.485
• Mol File: 84131-75-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1β,4α-bis(benzyloxy)-1,2,3,4,4aβ,5,8,8aα-octahydronaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 1β,4α-bis(benzyloxy)-1,2,3,4,4aβ,5,8,8aα-octahydronaphthalene(84131-75-9)
• EPA Substance Registry System: 1β,4α-bis(benzyloxy)-1,2,3,4,4aβ,5,8,8aα-octahydronaphthalene(84131-75-9)

Safety Data

• Hazardous Substances Data: 84131-75-9(Hazardous Substances Data)

Upstream product

• 2906-93-6 (+/-)-1,4,5,8,9,10-trans-hexahydronaphthalene-1,4-dione 
• 100-44-7 benzyl chloride 
• 3198-50-3 (-)-(1S,4S,9R)-Δ⁶-trans-Octalin-1,4-diol 

Downstream Products

• 79782-47-1 C₃₉H₅₂N₂O₆S 
• 79782-47-1 (4aα,8aβ)-5β,8α-bis(benzyloxy)-2β-methyl-3-oxo-1β-<3-(1-ethoxyethoxy)propyl>decahydronaphthalene tosylhydrazone 
• 79782-44-8 Methanesulfonic acid (1R,4aR,5S,8S,8aR)-5,8-bis-benzyloxy-1-[3-(1-ethoxy-ethoxy)-propyl]-3-oxo-decahydro-naphthalen-2-ylmethyl ester 
• 79782-44-8 Methanesulfonic acid (1R,4aR,5S,8S,8aR)-5,8-bis-benzyloxy-1-[3-(1-ethoxy-ethoxy)-propyl]-3-oxo-decahydro-naphthalen-2-ylmethyl ester 
• 79782-46-0 (4aS,5S,8S,8aR)-5,8-Bis-benzyloxy-4-[3-(1-ethoxy-ethoxy)-propyl]-3-methyl-4a,5,6,7,8,8a-hexahydro-1H-naphthalen-2-one 
• 79782-43-7 (4R,4aR,5S,8S,8aR)-5,8-Bis-benzyloxy-4-[3-(1-ethoxy-ethoxy)-propyl]-3-hydroxymethyl-octahydro-naphthalen-2-one 
• 79782-43-7 (4aα,8aβ)-5β,8α-bis(benzyloxy)-2(hydroxymethyl)-3-oxo-1β-<3-(1-ethoxyethoxy)propyl>decahydronaphthalene 
• 79782-45-9 (4R,4aR,5S,8S,8aR)-5,8-Bis-benzyloxy-4-[3-(1-ethoxy-ethoxy)-propyl]-3-methylene-octahydro-naphthalen-2-one 
• 79782-45-9 (4aα,8aβ)-5β,8α-bis(benzyloxy)-2-methylene-3-oxo-1β-<3-(1-ethoxyethoxy)propyl>decahydronaphthalene 
• 79782-42-6 (3R,4R,4aR,5S,8S,8aR)-5,8-Bis-benzyloxy-4-[3-(1-ethoxy-ethoxy)-propyl]-3-methyl-octahydro-naphthalen-2-one 
• 79782-42-6 (3S,4R,4aR,5S,8S,8aR)-5,8-Bis-benzyloxy-4-[3-(1-ethoxy-ethoxy)-propyl]-3-methyl-octahydro-naphthalen-2-one 
• 79782-42-6 (3R,4R,4aR,5S,8S,8aR)-5,8-Bis-benzyloxy-4-[3-(1-ethoxy-ethoxy)-propyl]-3-methyl-octahydro-naphthalen-2-one 
• 79782-42-6 (4aα,8aβ)-5β,8α-bis(benzyloxy)-2α-methyl-3-oxo-1β-<3-(1-ethoxyethoxy)propyl>decahydronaphthalene 
• 79782-48-2 (1S,4S,4aR,5S,6S,8aR)-1,4-Bis-benzyloxy-5-[3-(1-ethoxy-ethoxy)-propyl]-6-methyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalene 

Relevant articles and documents

Total synthesis of the hypocholesterolemic agent compactin

A total synthesis of ( plus )-compactin (ML-236B), a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, is presented. The key chiral hexahydronaphthalene intermediate was efficiently synthesized in 70% overall yield from the optically active diol. In turn, the diol was obtained via microbiological reduction of the racemic dione. ( plus )-Compactin was prepared in 14 steps from the chiral hexahydronaphthalene intermediate in 0. 8% yield. Refs.