84134-14-5Relevant academic research and scientific papers
Trans-dichlorobis(N-p-tolylpyridin-2-amine)palladium(II): Synthesis, structure, fluorescence features and DNA binding
Kundu, Suman,Maity, Suvendu,Bhadra, Ranjan,Ghosh, Prasanta
, p. 1443 - 1449 (2011/12/02)
Reaction of N-p-tolylpyridin-2-amine (LMe) with H 2PdCl4 in boiling acetonitrile and ethanol solvents mixture (1:1) affords trans-Pd(LMe)2Cl2 (1) in high yield. (1) is substantiated by spectral data, single crystal X-ray structure determination, etc. Both (LMe) and (1) absorb strongly in the UV region (λmax, nm (ε, 104 M -1cm-1), DCM: (LMe), 310 (1.97), 276 (4.95); (1), 320 (4.36), 270 (6.98). (LMe) is brightly fluorescent due to intra-ligand charge transfer singlet excited state (λex = 332 nm, λem = 400 nm; Φ = 0.621 measured with respect to anthracene) as elucidated by DFT and TD DFT calculations. In (1), the luminescence of (LMe) is significantly ( 97 %) quenched (Φ = 0.016) and the fluorescence parameters are red shifted (λex = 378 nm, λem = 430 nm). Binding of (1) to CT-DNA has been investigated by UV-vis spectrum confirming a significant interaction with the intrinsic binding constant as Kb = 9.78 × 105 M-1 and CT-DNAethidium bromide fluorescence quenching experiment giving the apparent binding constant as Kapp = 9.02 × 10 5 M-1.
