84145-70-0

Basic information

• Product Name: 3-[(2-amino-4-fluorophenyl)amino]propan-1-ol
• Synonyms: 3-[(2-amino-4-fluorophenyl)amino]propan-1-ol;3-[(2-Amino-4-fluorophenyl)amino]-1-propanol;Einecs 282-298-4
• CAS NO: 84145-70-0
• Molecular Formula: C9H13FN2O
• Molecular Weight: 184.2107232
• EINECS: 282-298-4
• Mol File: 84145-70-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 373.9°C at 760 mmHg
• Flash Point: 180°C
• Appearance: /
• Density: 1.262g/cm³
• Vapor Pressure: 2.96E-06mmHg at 25°C
• Refractive Index: 1.614
• CAS DataBase Reference: 3-[(2-amino-4-fluorophenyl)amino]propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(2-amino-4-fluorophenyl)amino]propan-1-ol(84145-70-0)
• EPA Substance Registry System: 3-[(2-amino-4-fluorophenyl)amino]propan-1-ol(84145-70-0)

Safety Data

• Hazardous Substances Data: 84145-70-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H13FN2O/c10-7-2-3-9(8(11)6-7)12-4-1-5-13/h2-3,6,12-13H,1,4-5,11H2

Relevant articles and documents

BENZIMIDAZOLE DERIVATIVES HAVING DOPAMINERGIC ACTIVITY

Pharmaceutically active benzimidazole derivatives are disclosed comprising compounds of the formula: STR1 particularly wherein X is nitrogen, R. sup.1 is phenyl or heteroaryl, and one of R 2 or R 3 is hydroxy. Said compounds have D4 dopaminergic receptor binding activity and consequently are useful as active ingredients in pharmaceutical compositions and methods of treatment for sleep disorders, sexual disorders, gastrointestinal disorders, psychosis, affective psychosis, nonorganic psychosis, personality disorders, psychiatric mood disorders, conduct and impulse disorders, schizophrenic and schizoaffective disorders, polydipsia, bipolar disorders, dysphoric mania, anxiety and related disorders, obesity, emesis, bacterial infections of the CNS, learning disorders, memory disorders, Parkinson's disease, depression, extrapyramidal side effects from neuroleptic agents, neuroleptic malignant syndrome, hypothalamic pituitary disorders, ocular disorders, congestive heart failure, chemical dependencies, vascular and cardiovascular disorders, dystonia, tardive dyskinesia, Gilles De La Tourette's syndrome and other hyperkinesias, dementia, ischemia, Parkinson's disease, akathesia and other movement disorders, hypertension and diseases caused by a hyperactive immune system such as allergies and inflammation in a mammal.