84186-23-2

Basic information

• Product Name: Ethyl 2-Cyano-3-(2-fluorophenyl)acrylate
• Synonyms: Ethyl 2-Cyano-3-(2-fluorophenyl)acrylate
• CAS NO: 84186-23-2
• Molecular Formula: C₁₂H₁₀FNO₂
• Molecular Weight: 219.2117032
• Mol File: 84186-23-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethyl 2-Cyano-3-(2-fluorophenyl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-Cyano-3-(2-fluorophenyl)acrylate(84186-23-2)
• EPA Substance Registry System: Ethyl 2-Cyano-3-(2-fluorophenyl)acrylate(84186-23-2)

Safety Data

• Hazardous Substances Data: 84186-23-2(Hazardous Substances Data)

Upstream product

• 446-52-6 2-Fluorobenzaldehyde 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 129115-58-8 C₁₇H₁₂FN₃O₂ 
• 111861-31-5 2-Amino-4-(2-fluoro-phenyl)-7-hydroxy-4H-chromene-3-carboxylic acid ethyl ester 
• 773084-46-1 2-cyano-3-(2-fluoro-phenyl)-propionic acid ethyl ester 
• 1372800-95-7 (1S,2R,3R)-triethyl 2-cyano-2'-fluoro-1,2,3,6-tetrahydro-[1,1'-biphenyl]-2,3,4-tricarboxylate 
• 1239019-89-6 (1R,2R)-diethyl 1-cyano-2-(2-fluorophenyl)cyclopent-3-ene-1,3-dicarboxylate 
• 84186-27-6 2-amino-3-ethoxycarbonyl-4-(2-fluorophenyl)-4H-naphtho<2,1-b>pyran 
• 446-52-6 2-Fluorobenzaldehyde 

Relevant articles and documents

Towards organo-click reactions: Development of pharmaceutical ingredients by using direct organocatalytic bio-mimetic reductions

Economic and environmentally friendly bio-mimetic one-pot three and four-component Knoevenagel-hydrogenation (K-H), five-component Knoevenagel-hydrogenation-alkylation (K-H-A) and six-component Knoevenagel-hydrogenation-alkylation-Huisgen cycloaddition (K-H-A-HC) reactions of aldehydes, CH-acids, o-phenylenediamine, alkyl halides and azides using proline, proline-metal carbonate and proline-metal carbonate-Cu I-catalysis, respectively have been developed. Many of K-H and K-H-A compounds have direct application in pharmaceutical chemistry. The Royal Society of Chemistry.