84194-36-5

Basic information

• Product Name: 2-Chloro-4-fluorobenzaldehyde
• Synonyms: TIMTEC-BB SBB003983;2-CHLORO-4-FLUOROBENZALDEHYDE;2-Chloro-4-Flouorobenzaldehyde;2-Chloro-4-fluorobenzaldehyde 97%;2-Chloro-4-fluorobenzaldehyde97%;2-Chloro-4-fluorobenzaldehyde ,98%
• CAS NO: 84194-36-5
• Molecular Formula: C₇H₄ClFO
• Molecular Weight: 158.56
• Product Categories: Fluorin-contained benzaldehyde series;Aromatic Aldehydes & Derivatives (substituted);Benzaldehyde;Fluorobenzene;Miscellaneous;Adehydes, Acetals & Ketones;Chlorine Compounds;Fluorine Compounds;Aldehydes;C7;Carbonyl Compounds;Azaindoles
• Mol File: 84194-36-5.mol
• Article Data: 8

Chemical Properties

• Melting Point: 60-63 °C(lit.)
• Boiling Point: 118-120 °C50 mm Hg(lit.)
• Flash Point: >110°C
• Appearance: white to slightly yellow crystalline
• Density: 1.3310 (estimate)
• Storage Temp.: Refrigerator
• Sensitive: Air Sensitive
• BRN: 3537704
• CAS DataBase Reference: 2-Chloro-4-fluorobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-4-fluorobenzaldehyde(84194-36-5)
• EPA Substance Registry System: 2-Chloro-4-fluorobenzaldehyde(84194-36-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 84194-36-5(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 84194-36-5 differently. You can refer to the following data:
1. 2-Chloro-4-fluorobenzaldehyde is a reactant in the regio- and stereoselective preparation of spiro[pyrrolidinoxindoles].
2. 2-Chloro-4-fluorobenzaldehyde may be used in the synthesis of substituted α-cyanocinnamic acid, via Knoevenagel condensation reaction. It may be used in the synthesis of 2-(2-benzimidazolyl)-3-(2-chloro-4-fluorophenyl)acrylonitrile.

Chemical Properties

white to slightly yellow crystalline

General Description

2-Chloro-4-fluorobenzaldehyde is a halogen substituted benzaldehyde.

InChI:InChI=1/C7H4ClFO/c8-7-3-6(9)2-1-5(7)4-10/h1-4H

Upstream product

• 45767-66-6 2-chloro-4-fluorobenzylbromide 
• 874-42-0 2,4-dichlorobenzaldeyhde 
• 459-57-4 4-fluorobenzaldehyde 
• 93286-22-7 2‐chloro‐4‐fluorobenzyl chloride 
• 208186-84-9 (2-chloro-4-fluorophenyl)methanol 
• 167758-87-4 ethyl 2-chloro-4-fluorobenzoate 
• 112135-96-3 2-chloro-4-fluorobenzal bromide 
• 452-73-3 2-chloro-4-fluorotoluene 

Downstream Products

• 698356-74-0 2-chloro-4-(2-chloro-4-methoxy-phenoxy)-benzaldehyde 
• 698356-65-9 2-chloro-4-(3-chloro-4-methoxy-phenoxy)-benzaldehyde 
• 516481-15-5 2-[2-Chloro-4-(4-chloro-phenoxy)-phenyl]-1H-benzoimidazole-5-carboxylic Acid Amide 
• 174603-37-3 3-(2-chloro-4-fluorophenyl)-2-propenoic acid 
• 99329-85-8 2-chloro-4-fluoro-5-nitro-benzaldehyde 
• 112108-68-6 1-(2-chloro-4-fluorophenyl)ethan-1-ol 
• 183678-42-4 N-(2-chloro-4-fluorobenzylidene)-2'-methoxyaniline 
• 1005494-40-5 (E)-2-chloro-4-fluorostyryl-4-methoxybenzylsulfone 
• 935430-67-4 (E)-3-(2-chloro-4-(4-fluorophenylthio)-phenyl)acrylic acid 
• 935430-70-9 (E)-3-(2-chloro-4-(2-methoxyphenylthio)phenyl)acrylic acid 
• 1006727-28-1 2-Chloro-4-(3-chlorophenylthio)benzaldehyde 

Relevant articles and documents

Preparation method of 2-chloro-4-fluoro-5-nitrobenzaldehyde

The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of 2-chloro-4-fluoro-5-nitrobenzaldehyde. The method comprises the following steps: taking 2-chloro-4-fluorotoluene as a raw material, introducing ch

TEMPO-mediated oxidation of primary alcohols to aldehydes under visible light and air

A homogeneous visible light photoredox TEMPO-mediated selective oxidation of primary alcohols to the corresponding carbonyl compounds was developed using molecular oxygen from air as the terminal oxidant. Ru(bpy)3(PF 6)2 (bpy: bipyridyl) and Ir(dtb-bpy)(ppy) 2(PF6) (dtb-bpy: 4,4′-di-tert-butyl-2,2′- bipyridyl; ppy: 2-phenylpyridine) were used as the sensitizers. A homogeneous visible light photoredox TEMPO-mediated selective oxidation of primary alcohols to the corresponding carbonyl compounds was developed. Molecular oxygen from air was the terminal oxidant. Copyright

'HALEX' FLUORINATION OF CHLORINATED BENZALDEHYDES AND BENZOYL CHLORIDES

Spray-dried potassium fluoride, suspended in sulpholane at 220 degC, converted 2,4- and 2,6-dichlorobenzaldehyde into the corresponding difluoroaldehydes (yields ca. 65percent).Small amounts of the mono-substituted products (2-chloro-4-fluoro- + 4-chloro-2-fluorobenzaldehyde, and 2-chloro-6-fluoro-benzaldehyde, respectively) were also produced.Similar treatment of the 3,4-dichloro-analogue gave 3-chloro-4-fluorobenzaldehyde (yield 98percent, conversion 68percent), but 2- and 4-chlorobenzaldehyde gave very poor yields (ca. 5percent) of the 2- and 4-fluoro-derivatives. 2-Fluoro-, 4-fluoro- and 3-chloro-4-fluorobenzoyl fluoride were obtained (yields 60-65percent) by heating the corresponding chlorobenzoyl chlorides with potassium fluoride in sulpholane.