84207-85-2Relevant academic research and scientific papers
Method for synthesizing isohexitol ester
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Paragraph 0010; 0043-0048; 0053-0054, (2021/05/05)
The invention discloses a method for synthesizing isohexitol ester, which is characterized in that a material containing hexitol and an esterifying agent is contacted with a solid acid catalyst in the presence of an aprotic solvent, and the isohexitol ester is obtained through one-pot one-step reaction. The method is especially suitable for the reaction of directly synthesizing the isohexitol ester, especially isosorbide ester, from hexitol, especially sorbitol, the total yield of the obtained isohexitol ester is 80% or above, and the yield of the isosorbide dicarboxylate reaches 60% or above.
METHOD FOR MEASURING REACTION RATIO OF ISOSORBIDE ALKANOATE
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Paragraph 0081; 0082, (2017/06/02)
The present invention relates to a method to measure a reaction ratio of an isosorbide alkanoate which rapidly and easily measures the reaction ratio of an isosorbide alkanoate produced through an ester reaction using a proton nuclear magnetic resonance analysis; and easily optimizes production conditions when the isosorbide alkanoate is produced by the ester reaction. The method to measure the reaction ratio of the isosorbide alkanoate comprises: a step of determining peak A, B, C, and D by performing the proton nuclear magnetic resonance analysis of the isosorbide alkanoate; and a step of calculating the reaction ratio of an isosorbide hexanoate.COPYRIGHT KIPO 2016
Regioselective Acylation of 1,4:3,6-Dianhydro-D-glucitol
Stoss, Peter,Merrath, Peter,Schlueter, Guenther
, p. 174 - 176 (2007/10/02)
Acylation of 1,4:3,6-dianhydro-D-glucitol with anhydrides in the presence of heavy metal salts affords 5-endo-acylates with high regioselectivity, without detectable amounts of the isomeric 2-acylates.Acyl group migration occurs with preference for the 2-exo-position, on heating an acylation mixture, which contains varying amounts of 1,4:3,6-dianhydro-D-glucitol, 2- and 5-monoacylate and 2,5-diacylate, in the presence of reesterification catalysts and whilst distilling off the lower boiling 2-acylate.
