84212-23-7Relevant academic research and scientific papers
Cyclisation of benzylaminonitriles. Part 8. Anhydrous hydrogen fluoride as cyclising agent
Euerby, Melvin R.,Gavin, James P.,Olugbade, Tiwalade A.,Patel, Sanjay S.,Waigh, Roger D.
, p. 545 - 554 (2007/10/02)
The preferred cyclisation pathway for benzylaminonitriles in anhydrous HF is through a spiro intermediate, as it is in sulphuric acid.Unlike sulphuric acid, HF can be used in the cyclisation of N-alkyl benzylaminonitriles to give N-alkyl isoquinolinones a
