84227-79-2

Basic information

• Product Name: 1H-Benzimidazole,1-(oxiranylmethyl)-(9CI)
• Synonyms: 1H-Benzimidazole,1-(oxiranylmethyl)-(9CI)
• CAS NO: 84227-79-2
• Molecular Formula: C₁₀H₁₀N₂O
• Molecular Weight: 174.1992
• Product Categories: BENZIMIDAZOLE
• Mol File: 84227-79-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Benzimidazole,1-(oxiranylmethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole,1-(oxiranylmethyl)-(9CI)(84227-79-2)
• EPA Substance Registry System: 1H-Benzimidazole,1-(oxiranylmethyl)-(9CI)(84227-79-2)

Safety Data

• Hazardous Substances Data: 84227-79-2(Hazardous Substances Data)

Upstream product

• 51-17-2 benzoimidazole 
• 106-89-8 epichlorohydrin 

Relevant articles and documents

Heterocyclic chitosan oligosaccharide derivative and synthesis method thereof

The invention provides a heterocyclic chitosan oligosaccharide derivative and a synthesis method thereof. The method comprises the following concrete steps that (1) a heterocyclic compound is added into ethyl alcohol to be dissolved; after the solution is clear, hexadecyl trimethyl ammonium bromide and sodium hydroxide are added; after the stirring at normal temperature is performed, epoxy chloropropane is dropwise added; stirring is performed for 1.5 to 3h until white solids occur; when the white solids are not increased, reaction stops; a solid and liquid mixture is obtained; (2) chitosan oligosaccharide is added into distilled water to be dissolved; the solid and liquid mixture in the step (1) is added; constant-temperature stirring is performed for 3 to 5h at 60 to 80 DEG C; cooling is performed to room temperature, ethyl alcohol is added; still standing is performed for 12 to 15h; pressure reduction filtering is performed to obtain solids; the solids are washed twice by ethanol; drying is performed in a drying box. The prepared heterocyclic chitosan oligosaccharide derivative has good antibiotic activity and achieves a certain inhibiting effect on tobacco black shanks and corn stalk rot. The heterocyclic chitosan oligosaccharide derivative has good lipid solubility and water solubility, and can be easily absorbed by animals and plants; the activity is high.

Synthesis and Properties of N-2,3-Epoxypropyl Imidazole and Bisimidazole Derivatives

A number of mono- and bis-(2,3-epoxypropyl) derivatives of imidazoles, benzimidazoles, and bisbenzimidazoles, as well as their salts, were synthesized starting from corresponding azoles and 1-chloro-2,3-epoxypropane. On the basis of 1H NMR and IR spectral data, one of the y-protons in the oxirane ring is presumed to participate in intramolecular H-π interaction with aromatic rings of the azoles. The obtained compounds exhibit antitumor activity and luminescent properties and are potential hardeners and cohardeners for epoxy resins.