84243-59-4

Basic information

• Product Name: 6-<4-(1H-imidazole-1-yl)phenyl>-3(2H)-pyridazinone
• Synonyms: 6-<4-(1H-imidazole-1-yl)phenyl>-3(2H)-pyridazinone
• CAS NO: 84243-59-4
• Molecular Weight: 238.249
• Mol File: 84243-59-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 6-<4-(1H-imidazole-1-yl)phenyl>-3(2H)-pyridazinone(CAS DataBase Reference)
• NIST Chemistry Reference: 6-<4-(1H-imidazole-1-yl)phenyl>-3(2H)-pyridazinone(84243-59-4)
• EPA Substance Registry System: 6-<4-(1H-imidazole-1-yl)phenyl>-3(2H)-pyridazinone(84243-59-4)

Safety Data

• Hazardous Substances Data: 84243-59-4(Hazardous Substances Data)

Upstream product

• 10041-06-2 4'-(imidazol-1-yl)acetophenone 
• 298-12-4 Glyoxilic acid 
• 84243-57-2 4-(1H-imidazol-1-yl)-γ-oxobenzenebutanoic acid 
• 84243-58-3 imazodan 
• 366-77-8 4-(4-fluorophenyl)-4-oxopropionic acid 

Downstream Products

• 102618-17-7 6-<4-(1H-imidazol-1-yl)phenyl>-3-(phenylmethyl)-1,2,4-triazolo<4,3-b>pyridazine monohydrochloride 
• 102618-13-3 6-(4-Imidazol-1-yl-phenyl)-[1,2,4]triazolo[4,3-b]pyridazine; hydrochloride 
• 102618-11-1 3-hydrazino-6-<4-(1H-imidazol-1-yl)phenyl>-3(2H)-pyridazine monohydrochloride 
• 102634-81-1 6-<4-(1H-imidazol-1-yl)phenyl>-3-(trifluoromethyl)-1,2,4-triazolo<4,3-b>pyridazine 
• 102618-16-6 6-(4-Imidazol-1-yl-phenyl)-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazine 
• 102618-15-5 3-Ethyl-6-(4-imidazol-1-yl-phenyl)-[1,2,4]triazolo[4,3-b]pyridazine 
• 102618-20-2 6-<4-(1H-imidazol-1-yl)phenyl>-1,2,4-triazolo<4,3-b>pyridazin-3(2H)-one 
• 102618-14-4 6-(4-Imidazol-1-yl-phenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazine 
• 102618-18-8 2-[6-(4-Imidazol-1-yl-phenyl)-pyridazin-3-ylamino]-ethanol 
• 102618-19-9 2,3-dihydro-6-<4-(1H-imidazol-1-yl)phenyl>imidazo<1,2-b>pyridazine 
• 102618-12-2 3-<4-(1H-imidazol-1-yl)phenyl>-6-(1-methylhydrazino)pyridazine 
• 93702-54-6 3-<4-(1H-imidazol-1-yl)phenyl>-6-(methylthio)pyridazine 
• 102618-10-0 3-chloro-6-<4-(1H-imidazol-1-yl)phenyl>-3(2H)-pyridazine 
• 97150-65-7 4-amino-6-<4-(1H-imidazol-1-yl)phenyl>-3(2H)pyridazinone 

Relevant articles and documents

One-pot preparation of 6-substituted 3(2H)-pyridazinones from ketones

A one-pot process for the preparation of 6-phenyl-3(2H)-pyridazinone from acetophenone and glyoxylic acid has been investigated and shown to have wide utility in the preparation of 6- and 5,6-substituted 3(2H)-pyridazinones. Limitations to the process encountered with 2'-hydroxyacetophenone and with basic hetero-aromatic ketones have been overcome, and the processes described offer the rapid and efficient synthesis of many 6-substituted pyridazinones from readily available ketones.

Cardiotonic Agents. 2. Synthesis and Structure-Activity Relationships of 4,5-Dihydro-6--3(2H)-pyridazinones: A New Class of Positive Inotropic Agents

A series of 4,5-dihydro-6--3(2H)-pyridazinones and related compounds were synthesized and evaluated for positive inotropic activity.Most members of this series produced dose-related increases in myocardial contractility that we