84244-48-4Relevant academic research and scientific papers
Facile synthesis and in vitro properties of 1-alkyl- and 1-alkyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline derivatives on PC12 cells
Kitabatake, Michikazu,Nagai, Junko,Abe, Kenji,Tsuchiya, Yukihiro,Ogawa, Keita,Yokoyama, Takashi,Mohri, Kunihiko,Taguchi, Kyoji,Horiguchi, Yoshie
, p. 4034 - 4043 (2009)
The synthesis of several 1-alkyl-1,2,3,4-tetrahydroisoquinolines, which may play an important role in Parkinson's disease, has been achieved by modified Pictet-Spengler cyclization of the formyliminium ion. The direct cytotoxicity and preventative effects
