84257-68-1

Basic information

• Product Name: 1(2H)-Phthalazinone, 4-methyl-2-[(4-methylphenyl)sulfonyl]-
• CAS NO: 84257-68-1
• Molecular Formula: C16H14N2O3S
• Molecular Weight: 314.365
• Mol File: 84257-68-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1(2H)-Phthalazinone, 4-methyl-2-[(4-methylphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Phthalazinone, 4-methyl-2-[(4-methylphenyl)sulfonyl]-(84257-68-1)
• EPA Substance Registry System: 1(2H)-Phthalazinone, 4-methyl-2-[(4-methylphenyl)sulfonyl]-(84257-68-1)

Safety Data

• Hazardous Substances Data: 84257-68-1(Hazardous Substances Data)

Upstream product

• 54145-23-2 4-methyl-1(2H)-phthalazinethione 
• 5004-48-8 1-methyl-3,4-dihydro-4-oxophthalazine 
• 84257-71-6 1-(ethoxycarbonylmethylthio)-4-methylphthalazine 

Relevant articles and documents

Substitution and Ring Closure Reactions of Phthalazine Derivatives

1-(Phenylthio)- and 1-(hydroxycarbonylmethylthio)-4-methylphthalazines were prepared from 1-chloro-4-methylphthalazines (1).A series of 2-benzyl- and benzenesulfonyl derivatives was prepared from the corresponding halides and 4-methyl-1(2H)-phthalazinone (4). 4-Methyl-1(2H)-phthalazinthione (6) was substituted at SH group to give 1-(benzylthio)- and 1-(ethoxycarbonylmethylthio)-4-methylphthalazines, 7 and 8 respectively.Treatment of hydrazine hydrate with 8 produced 1-hydrazino-4-methylphthalazine (10).However, when the latter compound was treated with 1 it gave 1,2-bis-(4-methylphthalazinyl)hydrazine.Treatment of 10 with aromatic aldehydes in glacial acetic acid gave the corresponding 3-phenyl-s-triazolo-6-methylphthalazines 13. 1-Hydrazino-4-methylphthalazine (10) underwent cyclization reactions with acetic anhydride, ethyl chloroformate, carbon disulphide, ethyl formate, ethyl oxalate and with nitrous acid to give the corresponding triazolo-, triazino- and tetrazolophthalazine compounds.