84261-48-3

Basic information

• Product Name: 3-benzyl-3-hydroxy-1-methylquinoline-2,4(1H,3H)-dione
• Synonyms: 3-benzyl-3-hydroxy-1-methylquinoline-2,4(1H,3H)-dione
• CAS NO: 84261-48-3
• Molecular Weight: 281.311
• Mol File: 84261-48-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3-benzyl-3-hydroxy-1-methylquinoline-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-3-hydroxy-1-methylquinoline-2,4(1H,3H)-dione(84261-48-3)
• EPA Substance Registry System: 3-benzyl-3-hydroxy-1-methylquinoline-2,4(1H,3H)-dione(84261-48-3)

Safety Data

• Hazardous Substances Data: 84261-48-3(Hazardous Substances Data)

Upstream product

• 72587-96-3 3-benzyl-4-hydroxy-1-methylquinolin-2(1H)-one 
• 94674-88-1 3-benzyl-3-chloro-1-methylquinoline-2,4(1H,3H)-dione 
• 773837-37-9 sodium cyanide 
• 141-43-5 ethanolamine 

Downstream Products

• 172604-63-6 3-hydroxy-1-methylquinolin-2(1H)-one 

Relevant articles and documents

Reaction of Tertiary 2-Chloroketones with Cyanide Ions: Application to 3-Chloroquinolinediones

3-Chloroquinoline-2,4-diones react with cyanide ions in dimethyl formamide to give 3-cyanoquinoline-2,4-diones in small yields due to the strong hindrance of the substituent at the C-3 atom. Good yields can be achieved if the substituent at this position

Reduction of 3-aminoquinoline-2,4(1H,3H)-diones and deamination of the reaction products

3-Aminoquinoline-2,4-diones were stereoselectively reduced with NaBH 4 to give cis-3-amino-3,4-dihydro-4-hydroxyquinolin-2(1H)-ones. Using triphosgene (=bis(trichloromethyl) carbonate), these compounds were converted to 3,3a-dihydrooxazolo[4,5-

Thermal rearrangement of 3-hydroxy-1H,3H-quinoline-2,4-diones to 3-acyloxy-2,3-dihydro-1H-indol-2-ones

3-Alkyl/aryl-3-hydroxy-1H,3H-quinoline-2,4-diones (2) were transformed into isomeric 3-acyloxy-2,3-dihydro-1H-indol-2-ones (3) by thermally induced molecular rearrangement. All products were characterized by their 1H NMR, 13C NMR, an