84278-06-8

Upstream product

• 84245-61-4 ethyl L,L-3-amino-2-piperidone-6-carboxylate 
• 84245-58-9 2-Benzyloxycarbonylamino-N-((S)-2-oxo-tetrahydro-furan-3-yl)-malonamic acid tert-butyl ester 
• 84245-59-0 (S)-5-(2-Hydroxy-ethyl)-3,6-dioxo-piperazine-2-carboxylic acid tert-butyl ester 
• 84245-60-3 (1S,4S)-3,6-Dioxo-2,5-diaza-bicyclo[2.2.2]octane-1-carboxylic acid tert-butyl ester 
• 1004-98-4 (1S,4S)-2,5-Diaza-bicyclo[2.2.2]octane-3,6-dione 

Relevant academic research and scientific papers

AMINO ACID DERIVATIVES THAT STABILIZE SECONDARY STRUCTURES OF POLYPEPTIDES. I. SYNTHESIS OF LL-3-AMINO-2-PIPERIDONE-6-CARBOXYLIC ACID (LL-Acp), A NOVEL BETA-TURN-FORMING AMINO ACID

A six-step synthesis is reported of LL-3-amino-2-piperidone-6-carboxylic acid from L-homoserine lactone and the mono-t-butyl ester of N-benzyloxycarbonylaminomalonic acid.Evidence of chiral integrity is discussed.