84292-27-3Relevant academic research and scientific papers
RICERCHE SU DERIVATI PIRIDOPIRIMIDINICI. Nota I - Sintesi di 4-(dialchilammino)-2H-piridopirimidin-2-oni.
Roma, G.,Ermili, A.,Braccio, M. Di,Mazzei, M.
, p. 747 - 758 (2007/10/02)
Reaction of the N,N-dialkylethoxycarbonylacetamide-POCl3 reactant with 2-aminopyridine in refluxing dichloroethane yielded 4-(dialkylamino)-2H-pyridopyrimidine-2-ones (IV) together with generally lower quantities of isomeric 2-(dialkylamino)-4H-pyridopyrimidin-4-ones (V).Some compounds (V) were obtained also by reaction of 2-chloro-4H-pyridopyrimidin-4-one (VI) with the suitable amine in confirmation of their structure.In addition, the differences in the properties and in the spectroscopic characteristics of the two classes of isomers are reported.
