84294-89-3Relevant academic research and scientific papers
Synthesis of chiral chromanols: Via a RuPHOX-Ru catalyzed asymmetric hydrogenation of chromones
Ma, Yujie,Li, Jing,Ye, Jianxun,Liu, Delong,Zhang, Wanbin
supporting information, p. 13571 - 13574 (2019/01/05)
Chiral chromanols and their derivatives have been synthesized via a RuPHOX-Ru catalyzed asymmetric hydrogenation of chromones in high yields, >20:1 drs and with up to 99.9% ee. Control experiments show that the reaction undergoes two sequential asymmetric hydrogenation steps of the CC and CO double bonds. The reaction could be performed on a gram-scale with a relatively low catalyst loading (up to 1000 S/C), and the resulting products can be transformed to several biologically active compounds.
Synthesis of 2-(2-phenylethyl)chromones
Goel, Sharda,Shashi,Makrandi
, p. 535 - 536 (2007/10/03)
2-(2-Phenylethyl)chromones have been obtained by selective reduction of double bond of the styryl group in 2-styrylchromones involving catalytic hydrogen transfer reaction using ammonium formate in the presence of Pd-C.
