843-12-9Relevant academic research and scientific papers
Pyrazoles and Isoxazoles Based Sulfanilamide and Phenazone as Antimicrobial Agents: Synthesis and Biological Activity
Moustafa,El-Sayed,El Rayes,Morsy,Abd-allah,Ismail,Abd El-Aal
, p. 2314 - 2320 (2020/01/08)
New pyrazole and pyridine derivatives have been synthesized from sulfanilamide and phenazone via diazotization and coupling with a wide range of α-CH acids followed by heterocyclization with hydrazine derivative, hydroxylamine and cyanoacetamide. The anti
Polysubstituted pyrazoles. Part 2: Sulphonamidophenylhydrazone-2-pyrazolin-4-ones and sulphonamidophenylazopyrazoles as potential anticancer agents.
Soliman,Shafik
, p. 436 - 439 (2007/10/08)
The synthesis of some new derivatives of 1-[4-nitrophenyl]-5-[4-substituted sulphonamidophenylhydrazono]-2-pyrazolin-4-ones and 3,5-dimethyl-4-[4-substituted sulphonamidophenylazo]-pyrazoles is described. Bromination of ethyl 2-[nitrophenylhydrazono]-3-oxobutyrates in dry benzene afforded the 4-bromo derivatives which upon cyclization gave high yields of the 4-hydroxpyrazoles. Many other new intermediates were prepared and the results of the UV and IR spectral studies are discussed.
