84348-40-3Relevant articles and documents
Latent Warheads for Targeted Cancer Therapy: Design and Synthesis of pro-Pyrrolobenzodiazepines and Conjugates
Vlahov, Iontcho R.,Qi, Longwu,Kleindl, Paul J.,Santhapuram, Hari K.,Felten, Albert,Parham, Garth L.,Wang, Kevin,You, Fei,Vaughn, Jeremy F.,Hahn, Spencer J.,Klein, Hanna F.,Vetzel, Marilynn,Reddy, Joseph A.,Nelson, Melissa,Nicoson, Jeff,Leamon, Christopher P.
, p. 2921 - 2931 (2017/12/26)
Pyrrolobenzodiazepines (PBDs) and their dimers (bis-PBDs) have emerged as some of the most potent chemotherapeutic compounds, and are currently under development as novel payloads in antibody-drug conjugates (ADCs). However, when used as stand-alone thera
Synthesis of trans(±)6-phenoxyacetamido-1-methylene-3,3-dicarboxymethyl-1-carbapenam
Herdewijn,Claes,Vanderhaeghe
, p. 2903 - 2907 (2007/10/02)
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