84353-55-9

Basic information

• Product Name: 1-(2,2,2-trifluoroacetyl)-3-<2-(2,2,2-trifluoroacetyloxy)-2-phenylethyl>urea
• Synonyms: 1-(2,2,2-trifluoroacetyl)-3-<2-(2,2,2-trifluoroacetyloxy)-2-phenylethyl>urea
• CAS NO: 84353-55-9
• Molecular Weight: 372.224
• Mol File: 84353-55-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2,2,2-trifluoroacetyl)-3-<2-(2,2,2-trifluoroacetyloxy)-2-phenylethyl>urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,2,2-trifluoroacetyl)-3-<2-(2,2,2-trifluoroacetyloxy)-2-phenylethyl>urea(84353-55-9)
• EPA Substance Registry System: 1-(2,2,2-trifluoroacetyl)-3-<2-(2,2,2-trifluoroacetyloxy)-2-phenylethyl>urea(84353-55-9)

Safety Data

• Hazardous Substances Data: 84353-55-9(Hazardous Substances Data)

Upstream product

• 84353-61-7 1,3-bis(2,2,2-trifluoroacetyl)-1-<2-(2,2,2-trifluoroacetyloxy)-2-phenylethyl>urea 
• 25017-52-1 (2-hydroxy-2-phenylethyl)urea 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 354-38-1 2,2,2-trifluoroacetamide 
• 84353-56-0 (E)-N-(2-phenylethenyl)-2,2,2-trifluoroacetamide 

Relevant articles and documents

Trifluoroacetylation and Subsequent Pyrolysis of 2-Amino-2-oxazolines

Treatment of 2-amino-5-phenyl-2-oxazoline (I) with trifluoroacetic anhydride gave 1,3-bis(2,2,2-trifluoroacetyl)-1-urea (II).Compound II was pyrolyzed at 120 deg C to give 2,2,2-trifluoroacetyl isocyanate (III) and 2,2,2-trifluoro-N-acetamide (IV).Compound II was readily hydrolyzed to give 1-(2,2,2-trifluoroacetyl)-3-urea (VI).Compound VI was pyrolyzed at 230 deg C to give 2,2,2-trifluoroacetamide (VII) and 2,2,2-trifluoro-N-(E)-styrylacetamide (VIII).It was considered that the formation of VIII proceeded through the intermediate 2-(2,2,2-trifluoroacetyloxy)-2-phenylethyl isocyanate (XI) or 1-(2,2,2-trifluoroacetyl)-3-(E)-styrylurea (XII), as shown in Chart 1.Keywords - 2-amino-2-oxazoline; trifluoroacetylation; pyrolysis; 1,3-bis(2,2,2-trifluoroacetyl)-1-alkylurea; O,N-bis(2,2,2-trifluoroacetyl)aminoethanol; 1-(2,2,2-trifluoroacetyl)-3-alkylurea; 1-(2,2,2-trifluoroacetyl)-3-alkenylurea