843646-72-0

Basic information

• Product Name: 3-(2-Acetamidyl)phenylboronic acid pinacol ester
• Synonyms: 3-(2-ACETAMIDYL)PHENYLBORONIC ACID PINACOL ESTER;2-(3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetaMide;3-(Carbamoylmethyl)phenylboronic Acid Pinacol Ester
• CAS NO: 843646-72-0
• Molecular Formula: C₁₄H₂₀BNO₃
• Molecular Weight: 261.127
• Product Categories: Aryl;Organoborons
• Mol File: 843646-72-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 444.1±38.0 °C(Predicted)
• Appearance: /
• Density: 1.09±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 16.16±0.40(Predicted)
• CAS DataBase Reference: 3-(2-Acetamidyl)phenylboronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-Acetamidyl)phenylboronic acid pinacol ester(843646-72-0)
• EPA Substance Registry System: 3-(2-Acetamidyl)phenylboronic acid pinacol ester(843646-72-0)

Safety Data

• Hazardous Substances Data: 843646-72-0(Hazardous Substances Data)

Usage

Description

3-(2-Acetamidyl)phenylboronic acid pinacol ester is a boronic acid pinacol ester derivative with the chemical formula C16H23BNO4. It features a phenylboronic acid group and an acetamidyl group, making it a versatile compound in organic synthesis and medicinal chemistry.

Uses

Used in Organic Synthesis:
3-(2-Acetamidyl)phenylboronic acid pinacol ester is used as a synthetic intermediate for the formation of carbon-carbon and carbon-heteroatom bonds. Its boronic acid functionality allows for the construction of complex molecular structures, facilitating the synthesis of various organic compounds.
Used in Medicinal Chemistry:
In the pharmaceutical industry, 3-(2-Acetamidyl)phenylboronic acid pinacol ester is used as a key building block in the development of biologically active compounds. Its unique structure and reactivity enable the creation of novel drug candidates with potential therapeutic applications.
Used in Drug Development:
3-(2-Acetamidyl)phenylboronic acid pinacol ester is utilized as a precursor in the synthesis of pharmaceuticals. Its versatility and reactivity contribute to the discovery and optimization of new drugs with improved efficacy and selectivity.
Overall, 3-(2-Acetamidyl)phenylboronic acid pinacol ester is a valuable chemical entity in the fields of organic synthesis and medicinal chemistry, playing a crucial role in the development of innovative pharmaceuticals and complex organic compounds.

Upstream product

• 60312-83-6 2-(3-bromophenyl)acetamide 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1383118-86-2 4-{6-[3-(2-amino-2-oxoethyl)phenyl]-8-(isobutylamino)imidazo[1,2-a]pyrazin-3-yl}-N-cyclopropylbenzamide 

Relevant articles and documents

(3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors

New (3-oxo)pyridazin-4-ylurea derivatives having the chemcial structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of the phosphodiesterase IV (PDE4).