84375-16-6Relevant academic research and scientific papers
S-tetrahydroprotoberberineoxidase, process for producing the same and use thereof
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, (2008/06/13)
The invention relates to the enzyme S-tetrahydroprotoberberineoxidase, which oxidizes selectively S-tetrahydroprotoberberines and S-1-benzyl-1,2,3,4-tetrahydroisoquinoline in the presence of oxygen, resulting in the corresponding protoberberines and 1-ben
Synthesis of (-)- and (+)-2-hydroxy-6-keto-N-methylmorphinans, their O-methyl ethers, and 2-deoxy congeners
Schmidhammer, Helmut,Brossi, Arnold
, p. 3055 - 3060 (2007/10/02)
Bischler-Napieralski cyclization of the known phenylacetamide 1, followed by selective ether cleavage of the 3,4-dihydroisoquinoline 2 and sodium borohydride reduction, afforded the tetrahydroisoquinoline 4.Optical resolution of 4 with tartaric acid gave
