84375-18-8Relevant academic research and scientific papers
Synthesis of (-)- and (+)-2-hydroxy-6-keto-N-methylmorphinans, their O-methyl ethers, and 2-deoxy congeners
Schmidhammer, Helmut,Brossi, Arnold
, p. 3055 - 3060 (2007/10/02)
Bischler-Napieralski cyclization of the known phenylacetamide 1, followed by selective ether cleavage of the 3,4-dihydroisoquinoline 2 and sodium borohydride reduction, afforded the tetrahydroisoquinoline 4.Optical resolution of 4 with tartaric acid gave
