84413-81-0 Usage
Uses
Used in Pharmaceutical Research:
(4R)-4-[(5S,7S,8S,9S,10S,12S,13R,14S,17R)-7,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid is used as a research compound for exploring its potential biological activity and applications in drug development. Its unique structure and stereochemistry may offer insights into the development of new therapeutic agents.
Used in Drug Development:
In the pharmaceutical industry, (4R)-4-[(5S,7S,8S,9S,10S,12S,13R,14S,17R)-7,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid is used as a lead compound for the development of new drugs. Its complex structure and the presence of hydroxy and methyl groups may provide opportunities for optimization and the discovery of novel therapeutic agents with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 84413-81-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,4,1 and 3 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 84413-81:
(7*8)+(6*4)+(5*4)+(4*1)+(3*3)+(2*8)+(1*1)=130
130 % 10 = 0
So 84413-81-0 is a valid CAS Registry Number.
InChI:InChI=1/C24H40O4/c1-14(7-10-21(27)28)16-8-9-17-22-18(13-20(26)24(16,17)3)23(2)11-5-4-6-15(23)12-19(22)25/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17+,18+,19+,20+,22+,23+,24-/m1/s1
84413-81-0Relevant academic research and scientific papers
DARSTELLUNG VON CHOLSAEURELACTONEN
Schulze, P. E.,Seeger, A.,Illi, V.
, p. 2815 - 2818 (2007/10/02)
The 8-membered cyclic 24,12-lactones of cholic- and deoxycholic acid, previously prepared only in poor yield are easily synthesized by the reaction of the appropriate acids with arylsulfonylchloride in pyridine.Chenodeoxycholic acid is converted into a di
7β,12β-dihydroxy-5β-cholan-24-oic acid as an internal standard for quantitative determination of bile acids by gas chromatography
Arimoto,Adachi,Yamaga
, p. 631 - 641 (2007/10/02)
In order to find an artificial internal standard compound for quantitative determination of bile acids by gas chromatography, 7α,12α-, 7α,12β-, 7β,12α- and 7β,12β-dihydroxy-5β-cholan-24-oic acids were chemically synthesized with cholic acid as the first starting material. The gas chromatographic retention time of 7β,12β-dihydroxy-5β-cholan-24-oic acid (ββ-isomer) was more different from that of natural bile acids than the other isomers. Moverover, ββ-isomer was extracted in the same fraction as the bile acids from urine, and no urinary substance had the same retention time as ββ-isomer. No artifact was produced from ββ-isomer during the analysis procedure. It was concluded that the ββ-isomer is an internal standard compound with certain advantages for the quantitative determination of bile acids in urine by gas chromatography, irrespective of the recovery rate during the analysis procedure.
