84428-15-9

Basic information

• Product Name: Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate
• Synonyms: 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoic Acid Ethyl Ester;Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate
• CAS NO: 84428-15-9
• Molecular Formula: C₁₂H₁₄O₄
• Molecular Weight: 222.23716
• Product Categories: Aromatics
• Mol File: 84428-15-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate(84428-15-9)
• EPA Substance Registry System: Ethyl 3-(3-Hydroxy-4-Methoxyphenyl)-2-propenoate(84428-15-9)

Safety Data

• Hazardous Substances Data: 84428-15-9(Hazardous Substances Data)

Usage

Chemical Properties

Off-white Solid

Uses

3-(3-Hydroxy-4-methoxyphenyl)-2-propenoic Acid Ethyl Ester (cas# 84428-15-9) is a compound useful in organic synthesis.

Upstream product

• 621-59-0 isovanillin 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 64-17-5 ethanol 
• 537-73-5 isoferulic acid 

Downstream Products

• 537-73-5 isoferulic acid 
• 3207-31-6 3-(3-acetoxy-4-methoxyphenyl)acrylic acid 
• 1267949-32-5 3-(3-hydroxy-4-methoxyphenyl)prop-2-yn-1-oic acid 
• 1267949-42-7 7,8-dihydroxy-4-(3-hydroxy-4-methoxyphenyl)-3,4-dihydrocoumarin 
• 84428-16-0 ethyl 3-(3'-hydroxy-4'-methoxyphenyl)propanoate 

Relevant articles and documents

Hypervalent-Iodine(III)-Mediated Tandem Oxidative Dearomatization/Aziridination of Phenolic Amines: Synthesis of Functionalized Unactivated Aziridines

A new hypervalent-iodine(III)-mediated tandem reaction involving oxidative dearomatization and in situ aziridination of phenolic amines is described, providing a mild and effective method for the assembly of structurally interesting and synthetically usef

Preparation method of neoflavonoids

The invention relates to the field of chemical synthesis, in particular to a preparation method of neoflavonoids. The preparation method is characterized by comprising the following steps of using substituted benzaldehyde as an initial raw material to be reacted with malonic acid to generate a substituted phenylacrylic acid compound; performing an addition reaction, an elimination reaction and the like on the substituted phenylacrylic acid compound, or performing acetylation so as to protect a phenolic hydroxyl group, then performing a bromination reaction and the elimination reaction so as to synthesize the substituted phenylpropiolic acid compound ; and using montmorillonite K-10 after being acidulated by sulfuric acid as a catalyst, enabling the substituted phenylpropiolic acid compound and a phenolic compound to perform a heating reaction so as to generate the neoflavonoids. Compared with the prior art, the preparation method of the neoflavonoids, disclosed by the invention, has the characteristics that raw materials are cheap, and easy to obtain, the operation is simple, the catalyst can be recovered for use, and the method is environmentally-friendly, the post-treatment is simple, and the production cost is low, and the method has a high popularization and application value.

Synthesis of some phenylpropanoid glycosides (PPGs) and their acetylcholinesterase/xanthine oxidase inhibitory activities

In this research, three categories of phenylpropanoid glycosides (PPGs) were designed and synthesized with PPGs isolated from Rhodiola rosea L. as lead compounds. Their inhibitory abilities toward acetylcholinesterase (AChE) and xanthine oxidase (XOD) were also tested. Some of the synthetic PPGs exhibited excellent enzyme inhibitory abilities.