84440-19-7Relevant articles and documents
SUBSTITUTED NITROGEN CONTAINING COMPOUNDS
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Page/Page column 85; 86, (2019/01/05)
Disclosed are compounds of Formula (I): or a salt thereof, Formula (II) wherein R1 is: or; each W is independently NR1b or O; Z is a bond or CHR1d; and R1, R2, Rd, R3a, R3b, L1, B, V, Y, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.
Investigation of copper-free alkyne/azide 1,3-dipolar cycloadditions using microwave irradiation
Chatkewitz, Lindsay E.,Halonski, John F.,Padilla, Marshall S.,Young, Douglas D.
supporting information, p. 81 - 84 (2017/12/28)
The prevalence of 1,3-dipolar cycloadditions of azides and alkynes within both biology and chemistry highlights the utility of these reactions. However, the use of a copper catalyst can be prohibitive to some applications. Consequently, we have optimized
MONOBACTAM ORGANIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS
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Paragraph 0456, (2015/11/10)
This invention pertains generally to antibacterial compounds of Formula I, as further described herein, and pharmaceutically acceptable salts and formulations thereof. In certain aspects, the invention pertains to methods of using such compounds to treat infections such as those caused by Gram-negative bacteria.