84446-29-7Relevant articles and documents
A mild titanium-catalyzed synthesis of functionalized amino coumarins as fluorescence labels
Wirtz, Lisa,Kazmaier, Uli
supporting information; experimental part, p. 7062 - 7065 (2012/01/05)
In contrast to Bronsted and other Lewis acids ClTi(OiPr)3 is especially suited to catalyze the formation of amino-substituted coumarins from aminophenols and functionalized β-oxo esters in a Pechmann condensation. This straightforward protocol allows the synthesis of fluorescence labels and false fluorescent neurotransmitters.