84447-04-1 Usage
Molecular Weight
380.45 g/mol; the compound's relative molecular mass based on the atomic weights of its constituent atoms.
Derivation
Mannitol-based; the compound is derived from mannitol, a naturally occurring sugar alcohol.
Modification
Tosyl group; the compound has been modified with a tosyl group, which increases its reactivity.
Utility
Organic synthesis; the compound is useful as a building block in the synthesis of other organic molecules.
Pharmaceutical potential
Antiproliferative and antiviral properties; the compound has been studied for its potential as a pharmaceutical compound with possible applications in the treatment of diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 84447-04-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,4,4 and 7 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 84447-04:
(7*8)+(6*4)+(5*4)+(4*4)+(3*7)+(2*0)+(1*4)=141
141 % 10 = 1
So 84447-04-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H18O7S/c1-8-2-4-9(5-3-8)21(17,18)19-7-11-13(16)12(15)10(6-14)20-11/h2-5,10-16H,6-7H2,1H3/t10-,11-,12-,13-/m1/s1
84447-04-1Relevant academic research and scientific papers
A simple O-sulfated thiohydroximate molecule to be the first micromolar range myrosinase inhibitor
Cerniauskaite, Deimante,Gallienne, Estelle,Karciauskaite, Henreta,Farinha, Andrea S.F.,Rousseau, Jolanta,Armand, Sylvie,Tatibou?t, Arnaud,Sackus, Algirdas,Rollin, Patrick
body text, p. 3302 - 3305 (2009/08/09)
New non-hydrolyzable analogues of glucosinolates have been prepared. Myrosinase inhibition was observed with modified aglycon moieties, even bulky phenothiazine analogue 6 gave reasonable inhibition. The simplest structure 8 derived from dimethylaminoethanethiol has shown to be the most potent inhibitor with an IC50 of 3.32 μM.
Ethambutol-sugar hybrids as potential inhibitors of mycobacterial cell-wall biosynthesis
Reynolds, Robert C.,Bansal, Namita,Rose, Jerry,Friedrich, Joyce,Suling, William J.,Maddry, Joseph A.
, p. 164 - 179 (2007/10/03)
Ethambutol is an established front-line agent for the treatment of tuberculosis, and is also active against Mycobacterium avium infection. However, this agent exhibits toxicity, and is considered to have low potency. The action of ethambutol on the mycoba
