844488-31-9

Upstream product

• 162749-93-1 4-[1H-imidazol-2-yl(1-methyl-1H-pyrrol-3-yl)methylene]-1-benzylpiperidine 
• 96-34-4 methyl chloroacetate 
• 162749-77-1 α-(1-methyl-1H-pyrrol-2-yl)-1-benzyl-4-piperidineacetonitrile 
• 162749-80-6 (1-methyl-1H-pyrrol-2-yl)(1-benzyl-4-piperidinyl)methanone 
• 844488-29-5 (1-benzyl-piperidin-4-yl)-(1-methyl-1H-pyrrol-3-yl)-methanone 
• 24437-41-0 1-methyl-2-pyrroleacetonitrile 
• 844488-30-8 (+/-)-α-1H-imidazol-2-yl-α-(1-methyl-1H-pyrrol-3-yl)-1-benzyl-4-piperidinemethanol 
• 844488-28-4 (1-benzylpiperidin-4-ylidene)(1-methyl-1H-pyrrol-2-yl)acetonitrile 

Relevant academic research and scientific papers

Norpiperidine imidazoazepines as a new class of potent, selective, and nonsedative H1 antihistamines

Clinical doses of available H1 antihistamines are limited mainly by sedative side effects. However, higher doses are often required to obtain optimal therapeutic activity, especially in dermatology. We report the synthesis of three norpiperidin

Antiallergic imidazoazepines

The present invention is concerned with novel imidazoazepines of formula STR1 the pharmaceutically acceptable addition salts and stereochemically isomeric forms thereof, wherein each of the dotted lines independently represents an optional bond; --A--B--