844504-99-0Relevant academic research and scientific papers
Novel 6-position modified 1-thioalkyl-lincosamines
O'Dowd, Hardwin,Lewis, Jason G.,Gordeev, Mikhail F.
, p. 2979 - 2981 (2008/09/20)
A general method for the synthesis of 6-position modified lincosamines via stereospecific nucleophilic addition to readily available galactose 6-nitrone has been developed. A new route for the stereospecific installation of thioalkyl groups at the 1-position was also developed. These methods allow access to a variety of new derivatives of antibacterial lincosamides.
