84455-90-3Relevant academic research and scientific papers
Heterocyclic Transformations. Part 5: Studies in Reactions of 6-Methyl-1,3-oxazine-2,4(3H)-dione with Arylamines - a Facile Synthesis of 1-Aryl-6-methyluracils
Singh, Harjit,Singh, Palwinder,Aggarwal, Pawan,Kumar, Subodh
, p. 731 - 736 (2007/10/02)
6-Methyl-1,3-oxazine-2,4(3H)-dione 1 reacts with 2 equiv. arylamines 3 at 150-160 deg C to give 1-aryl-6-methyluracils 5 or 1-aryl-3-(3-aryliminobutanoyl)ureas 4.The latter - as well as mixtures of 1 and 3 (2 equiv.) on refluxing, in isopentanol in some cases or in acetic acid in general - provide a facile synthesis of 5.The role of the stoichiometric excess of arylamines as against an equiv. of an alkylamine in similar reactions has been rationalized.
SYNTHESIS AND TRANSFORMATIONS OF 1-(4-HYDROXYPHENYL)DIHYDROURACILS
Baltrushis, R. S.,Beresnevichyus, Z. I. G.,Mitskyavichyus, V. Yu.
, p. 1089 - 1095 (2007/10/02)
N-(4-hydroxyphenyl)-β-alanine and its methyl derivatives, as well as p-hydroxy-phenylamino-β,β'-dipropionic acid, were obtained by the reaction of p-aminophenol with methyl acrylate and acrylic, methacrylic, and crotonic acids.The β-alanines were converte
