84462-91-9

Upstream product

• 108-13-4 malonodiamide 
• 84462-79-3 3-dimethylamino-2-(4-nitrophenyl)-2-propenal 
• 84462-80-6 1,2-Dihydro-2-oxo-5-(4-nitrophenyl)-3-pyridinecarbonitrile 
• 104-03-0 4-nitrobenzeneacetic acid 

Downstream Products

• 144296-74-2 5-(4-nitrophenyl)-2-oxo-3-amino-1,2-dihydropyridine 

Relevant academic research and scientific papers

New cardiotonic agents related to amrinone: Synthesis of 1,2-dihydro-5-arylpyridin-2-ones

For development of new cardiotonic agents a serie of 5-aryl-3,4-dihydropyridin-2(1H)-ones, related to amrinone have been prepared from methylquinolines, 2-arylacetic acid or 3-arylethanones by direct aminomethylenation and subsequent condensation-cyclizat

3-Amino-5-(hydroxy- and/or aminophenyl)-6-(lower-alkyl)-2(1H)-pyridinones and cardiotonic use thereof

1-R1 -3-amino-5-(3-R'-4-R"-phenyl)-6-R-2(1H)-pyridinones or salts thereof, which are useful as cardiotonics, where R1 is hydrogen, lower-alkyl, or lower-hydroxyalkyl, R is hydrogen or lower-alkyl, and, R' and R" are each hydrogen, hy